疏肝和胃法治疗慢性胃炎180例临床观察

Smoothing the Liver and Regulating the Stomach Treat Chronic Gastritis 108 Cases

[目的]观察疏肝和胃法治疗幽门螺杆菌相关性慢性胃炎的疗效及作用机制。[方法]将180例患者随机分为两组,对照组服用西药,治疗组服用疏肝和胃的中药。经过4周治疗,[结果]两组症状、体征改善情况,消除黏膜炎症、幽门螺杆菌根除率差异无显著性(P>0.05),但治疗组均高于对照组;治疗组不良反应出现率为3.3%,对照组为20.0%,两组差异有显著性(P<0.01)。[结论]疏肝和胃中药具有较好的杀灭幽门螺杆菌、消除黏膜炎症、减少复发的作用,不良反应少,可有效治疗幽门螺杆菌相关性慢性胃炎。

[Objective] To observe the therapeutic effect and mechanism of smoothing the liver and regulating the stomach for treatment of Helicobacter pylorum（Hp）-related chronic gastritis. [Methods] 180 case were randomly divided into a treatment group treated by oral administration of Chinese medicine,smoothing the liver and regulating the stomach, and a control group treated by western medicine, for 4 weeks. [Results] There was no significant difference in improvement of symptoms and signs,mucosa eliminating rate and eradication rate of Hp between the two groups（P〉0.05）, but the treatment group being higher than the control group;the adverse reaction rate was 3.3% in the treatment group and 20.0% in the control group with significant difference between the two groups （P〈0.01）. [Conclusion]Mechanism of smoothing the liver and regulating the stomach is better actions of killing Hp, promoting mucosa elimination, reducing recurrence with less adverse reaction, so it can effectively treat Hp-related chronic gastritis.