五花舒肝汤治疗失眠52例疗效观察

Wuhua Shugan Decoction Treat Insomnia 52 Cases

[目的]观察五花舒肝汤、阿普唑仑治疗失眠的临床疗效和不良反应。[方法]将102例失眠患者随机分为两组,中药治疗者组用五花舒肝汤加减治疗,西药对照组用阿普唑仑治疗,观察两组患者失眠缓解情况、不良反应发生情况。[结果]中药治疗组治愈10例,显效14例,有效19例,无效9例;西药对照组治愈11例,显效16例,有效17例,无效6例;治疗组与对照组之间治愈率、显效率、总有效率均无明显差异(P>0.05);不良反应中药治疗组9例,西药对照组19例,两组有明显差异(P<0.05)。[结论]中药可以有效缓解失眠,与苯二氮卓类药物阿普唑仑疗效相当;但中药不良反应更少,易于被患者接受。

[Objective] To observe the clinical effect and side effect of Wuhua Shugan Decoction and Alprazolam on insomnia. [Method] Randomly divide 102 cases into 2 groups, TCM treatment group takes revised Wuhua Shugan Decoction, the western medicine group Alprazolam, 4w as a course; observe their insomnia relieve and side effect. [Result] For the TCM treatment group, 10 cases were cured, 14 had marked effect, 19 effect, 9 no effect; for the other group, 11, 16, 17, and 6 respectively; there＇re no marked difference between the 2 groups on cure rate, marked effect rate and total effective rate（P〉0.05）;for the side effect, 9 in the TCM group, 19 in another group, with marked difference（P〈0.05）. [Conclusion] TCM has comparative effect on relieving insomnia with Alprazolam, but with fewer side effects, can be easily accepted by patients.