河南省结核杆菌药物敏感性试验质量控制结果分析

Quality evaluation on mycobacterium tuberculosis drug susceptibility test in Henan province

目的评价河南省药敏试验质量。方法按照WHO全球结核病耐药监测药敏试验质量控制要求,分析2001年-2007年WHO结核病跨国参比实验对河南省约敏质量控制的资料。结果河南省2001年-2004年四次药物敏感试验的质量控制结果平均—致性均高于90%;2005-2007年SM、INH、RFP、EMB平均一致性分别为90.0%、97.8%、96.7%和88.9%。结论河南省药敏试验质量已经到达了WHO的要求。

Obective To evaluate the quality of drug susceptibility testing（DST） of MTB in Henan provincial TB reference laboratory.Methods According to quality assurance programme of the global anti-tuberculosis drug resistance surveillance, to analysis proficiency testing results for DST from the WHO/IUATLD supranational reference in 2001-2007.Results the four years mean accordance rate of DST Of four first line anti-tuberculosis drug is all higher than 90 % in2001-2004,the three years mean accordance rate of SM、INH、RFP、EMB is 90.0 %、97.8 %、96.7 %and 88.9 % in2005-2007,respectiVely.Conclusion The quality of DST is credible in Henan provincial TB reference laboratory.