老年患者下呼吸道白色假丝酵母菌医院感染分析

Lower Respiratory Tract Nosocomial Infection by Candida albicans in Geriatric Inpatients

目的探讨老年患者医院内下呼吸道白色假丝酵母菌感染因素及耐药情况。方法统计2004-2006年医院内下呼吸道感染的老年住院患者,痰液检出白色假丝酵母菌146例,进行回顾性分析。结果老年患者医院内下呼吸道白色假丝酵母菌感染相关因素多,且白色假丝酵母菌的检出率逐年上升,近3年分别为25.2%、36.9%、39.9%;耐药率呈显著上升趋势,近3年分别为20.6%、41.8%、34.2%。结论要降低老年患者下呼吸道白色假丝酵母菌医院感染率,必须有效地控制感染诱发因素,合理使用抗菌药物。

OBJECTIVE To investigate the factors that result in lower respiratory tract infection by Candida albicans and the situation of drug resistance in geriatric inpatients. METHODS Clinical samples were collected from the geriatric inpatients with lower respiratory tract infection in our hospital from Jan 2004 to Dec 2006, and among them, 146 patients were found containing C. albicans in their sputum. Meanwhile retrospective analysis was made. RESULTS There were many factors resulting in lower respiratory tract nosoeomial infection by C. albicans in geriatric inpatients, and the detection rates of C. albicans increased year by year in the past three years were 25.2% ,36.9% and 39.9%, respectively. The drug resistance of C. albicans raised obviously at the same time was 20.6% ,41.8% and 34.2%, respectively. CONCLUSIONS It is necessary for reducing lower respiratory tract infection rates to efficiently control the C. albicans infection factors and to properly use antibiotics.