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Grb2的抑制在抗肿瘤治疗中的意义

Inhibitation of Grb2 and anti-tumor therapy
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摘要 生长因子受体连接蛋白-2（Grb2）是一种广泛表达的衔接蛋白，在多种肿瘤细胞中过度表达，对肿瘤的发生和发展具有重要影响，从而成为肿瘤治疗的靶向位点之一。因此，抑制Grb2在抗肿瘤治疗中具有广泛前景。 The growth factor receptor -bound protein-2 （Grb2） is an adapter protein in cells. Over expression of Grb2 is found in many kinds of tumor and plays an important role in tumor proliferation and progression. So it may he a molecular target for anti-tumor therapy.
作者 姚娜(综述) 叶韵斌(审校)
机构地区 福建医科大学教学医院(福建省肿瘤医院)肿瘤免疫研究室
出处 《肿瘤研究与临床》 CAS 2008年第11期790-792,共3页 Cancer Research and Clinic
基金 福建省医学创新课题资助项目（2007-CXB-1）
关键词 GRB2 肿瘤 治疗 Grb2 Neoplasms Therapy
分类号 R735.2 [医药卫生—肿瘤]
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参考文献30

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二级参考文献17

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肿瘤研究与临床
2008年 第11期

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