胰岛素瘤和甲状旁腺机能减退误诊癫痫病例分析

Analysis of insulinoma and hypoparathyroidism cases misdiagnosed to have epilepsy

目的分析胰岛素瘤及甲状旁腺功能减退症误诊为癫痫的病例并探讨误诊误治的原因。方法对自2000年到2007年收治的58例胰岛素瘤和18例甲状旁腺功能减退症患者的临床资料进行回顾分析。结果因发作性肢体抽搐和(或)意识不清而误诊为癫痫并行抗癫痫治疗的分别为:胰岛素瘤组14/58例(24.1%),平均误诊时间为(3.3±2.6)年;甲状旁腺功能减退症组4/18例(22.2%),平均误诊时间为(2.9±3.3)年。结论对于反复癫痫样抽搐发作和(或)意识不清者,尤其是经长期抗癫痫治疗效果欠佳者,应注意对胰岛素瘤和甲状旁腺功能减退症的筛查。

Objective To analysize the insulinoma and hypoparathyroidism cases which were misdiagnosed to have epilepsy and to investigate the cause of misdiagnosis and mistreatment. Methods The clinical data of 58 insulinoma cases and 18 hypoparathyroidism cases hospitalized in our hospital from 2000 to 2007 were analysized. ResultsIn insulinoma cases, the cases which were misdiagnosed to have epilepsy for the symptoms of spasm or unconscious were 14/58（24. 1% ）, and the duration of mistreatment was 3.3 ± 2.6 years. In hypoparathyroidism cases, the data were 4/18 （22.2%） and 2.9 ± 3.3 years. Conclusion To those patients with the symptoms of recurrent convulsive seizure and/or unconscious, especially with no response to antiepileptic therapy, the screening process about insulinoma and hypoparathy- roidism should be carried out.