马来西亚一个三级保健医院早产儿视网膜病变的筛查(英文)

Retinopathy of prematurity screening in a tertiary-care hospital in Malaysia

目的:本研究旨在确定马来西亚一个三级保健医院早产儿视网膜病变的发病率及发病趋势。方法:回顾分析在2003-2005年之间出生并进行ROP筛查的婴儿,记录每个患儿ROP的最严重分期。结果:我们对188名婴儿进行了筛查,平均出生体重1105.3±300.6g,平均妊娠期为29.2 ±2.6wk。这些婴儿整体的ROP发病率为29.18 % (55/188)。出生体重在750g及以下的婴儿发病率为76.2%。3a以来,低体重儿的数量及重型ROP病例数量呈现一个增长的趋势(P<0.05)。出生体重与婴儿受检数量之间存在负相关关系(P=0.000)。结论:随着低体重和小月分婴儿比例的增加,患ROP的患儿比例随之增加。

AIM. To determine the incidence and trend of retinopathy of prematurity （ROP） cases in a tertiary-care hospital in Malaysia. METHODS： This was a retrospective study of infants born in 2003 to 2005 who underwent screening for ROP. The outcome measures included the worst stage of ROP recorded for each patient. RESULTS. 188 infants were screened. Their mean birth weight was 1105.3 ±300.6 grams and mean gestation was 29.2 ±2.6 weeks. The overall incidence of ROP detection in these babies was 29.18 % （55/188）. The incidence was 76.2% for babies whose birth weight was 750 grams or less. The trend over the three years showed an increase in the number of smaller sized infants and an increase in the number of cases developing severe ROP （ P 〈 0.05）. There was negative correlation （ P = 0. 000） between the number of examinations performed on the infant and birth weight. Birth weight below 751 grams required 2.4 times more examinations than infants between 751 to 1250 .qrams. CONCLUSION. There was an increase in the percentage of cases detected to have ROP as the proportion of infants with lower birth weight and gestational age increased.