真菌性角膜炎29例诊疗体会

Experience of the diagnosis and treatment of fungal keratitis in 29 cases

目的:通过对29例真菌性角膜炎的诊疗,探讨避免其误诊和漏诊的方法。方法:对29例具有真菌性角膜炎临床特征的病例,采用100g/LKOH湿片镜检,查找真菌丝或孢子,并送真菌培养。一旦确诊,立即抗真菌治疗。结果:29例患者通过100g/LKOH湿片镜检和/或真菌培养均确诊为该病,经有效的抗真菌治疗取得较满意效果。结论:真菌性角膜炎的治疗效果与是否诊断及时、治疗合理密切相关。首诊时利用实验室检查,可以有效避免真菌性角膜炎的误诊和漏诊,并提高治愈率。

AIM： To discuss the method of avoiding the mis-diagnosis and missed diagnosis of fungal keratitis through the experience of the diagnosis and treatment in 29 cases. METHODS： The 100g/L KOH wet-film microscopy examination was used to 29 fungal keratitis cases with clinical features, to find the true mycelium or spores, and sent to be fungal cultured. Once diagnosed, the patients were treated by antifungal treatment immediately. RESULTS： Through the 100g/L KOH wet-film micros- copy examination and/or fungal culture, the 29 cases were diagnosed. And we got satisfactory results with an effective anti-fungal treatment. CONCLUSION： The treatment effect on fungal keratitis is close to the timely diagnosis and reasonable treatment. Using the laboratory examination in the first consultation can effectively avoid the misdiagnosis and missed diagnosis of fungal keratitis and improve the cure-rate.