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原发性胆汁性肝硬化17例临床分析

Clinical Review of 17 Primary Biliary Cirrhosis
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摘要 目的:分析原发性胆汁性肝硬化(PBC)患者的临床特征,以提高对该病诊治的认识。方法:分析17例PBC患者的一般资料、临床表现、生化指标、免疫学指标及病理学改变。结果:PBC主要累及中年女性,易合并干燥综合征(SS)。胆管酶升高及抗线粒体M2抗体阳性有助于本病诊断。治疗首选熊去氧胆酸,糖皮质激素、免疫抑制剂适用于合并SS者。结论:早期诊断、早期治疗PBC是防止发展为终末期肝硬化的关键。
出处 《华西医学》 CAS 2008年第1期126-127,共2页 West China Medical Journal
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参考文献5

  • 1Bach N,Odin JA.Primary biliary cirrhosis:a Mount Sinai Perspective[J].Mt Sinai J Med,2003,70:242-250.
  • 2Talwalkar JA,Lindor KD.Primary biliary cirrhosis[J].Lancet,2003,262:53-61.
  • 3Neuberger J.Primary biliary cirrhosis[J].Lancet,1997,350:875-879.
  • 4O′Donohue J,Williams R.Primary biliary cirrhosis[J].Q J Med,1996,89:5-13.
  • 5张烜,唐福林.原发性胆汁性肝硬化临床诊治的认识[J].中华风湿病学杂志,2004,8(6):324-326. 被引量:5

二级参考文献16

  • 1Bandin O, Courvalin JC, Poupon R, et al. Specificity and sensitivity of gp210 autoantibodies detected using an enzyme-linked immunosorbent assay and a synthetic polypeptide in the diagnosis of primary biliary cirrhosis. Hepatology, 1996, 23: 1020-1024.
  • 2Bach N, Odin JA. Primary biliary cirrhosis: a Mount Sinai perspective. Mt Sinai J Med, 2003, 70: 242-250.
  • 3Kamihira T, Shimoda S, Harada K, et al. Distinct costimulation dependent and independent autoreactive T-cell clones in primary biliary cirrhosis. Gastroenterology, 2003, 125: 1379-1387.
  • 4Mitchison HC, Palmer JM, Bassendine MF, et al. A controlled trial of prednisolone treatment in primary biliary cirrhosis: threeyear results. J Hepatol, 1992, 15: 336-344.
  • 5Leuschner M, Guldutuna S, You T, et al. Ursodeoxycholic acid and prednisolone versus ursodeoxycholic acid and placebo in the treatment of early stages of primary biliary cirrhosis. J Hepatol,1996, 25: 49-57.
  • 6Chan CW, Papatheodoridis GV, Goulis J, et al. Ursodeoxycholic acid and histological progression in primary biliary cirrhosis. J Hepatol, 2003, 39: 1094-1095.
  • 7Talwalkar JA, Lindor KD. Primary biliary cirrhosis. Lancet, 2003,262: 53-61.
  • 8Muratori P, Muratori L, Ferrari R, et al. Characterization and clinical impact of antinuclear antibodies in primary biliary cirrhosis. Am J Gastroenterol, 2003, 98: 431-437.
  • 9Ikuno N, Mackay IR, Jois J, et al. Antimitochondrial autoantibodies in saliva and sera from patients with primary biliary cirrhosis.J Gastroenterol Hepatol, 2001, t6: 1390-1394.
  • 10Metcalf JV, Mitchison HC, Palmer JM, et al. Natural history of early primary biliary cirrhosis. Lancet, 1996, 348: 1399-1402.

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