正常前列腺、前列腺癌的经直肠超声造影特点的研究

Study of the characteristics of normal prostate and prostatic carcinoma by transrectal contrast enhanced ultrasonography

目的:应用经直肠超声造影观察前列腺的正常内外腺组织及癌灶组织的造影增强起始时间及显影终止时间,观察其显影特点及差别,为超声诊断前列腺癌提供依据。方法:采用Bracco公司超声造影剂SonoVue,团注法,经直肠超声分别观察正常前列腺外腺组、正常前列腺内腺组、前列腺外腺癌灶组、前列腺内腺癌灶组造影增强起始时间及显影终止时间。结果:正常前列腺内腺组与外腺组造影增强起始时间无明显差别(P>0.05);前列腺内腺癌灶组与前列腺外腺癌灶组造影增强起始时间也无明显差别(P>0.05),但二者比正常前列腺内腺组与外腺组造影增强起始时间明显提前(P<0.01)。各组显影终止时间无明显差别(P>0.05)。结论:前列腺癌造影后提前显影,对鉴别正常前列腺组织及前列腺癌灶有重要价值。

Objective： To observe the characteristics and diff＇erence of the inner zone and outer zone of prostate gland, with the inner zone cancer and outer zone cancer by transreetal contrast enhanced ultrasonography. To provide more valuable information for early diagnosing of prostatic carcinoma. Methods： The ultrasound contrast agent was SonoVue （Bracco, Italian）. Instrument adopted was Esaote company Technos DUg. The starting time and the ending time of transrectal contrast enhanced ultrasonography in the prostate inner gland（16 cases）, the prostate outer gland（16 cases）, the prostate inner gland cancer lesion （8 cases）, and the prostate outer gland eaneer （11 cases） were observed. Results： There was no significant difference between the starting enhanced time of the prostate inner gland and the prostate outer gland, no significant difference between the starting enhanced time of the inner gland cancer lesion and the outer gland cancer lesion too, but the starting enhanced time of the inner gland cancer lesion and the outer gland cancer lesion was earlier than that of the prostate inner gland and the prostate outer gland, the wash out time of the prostate inner gland, the prostate outer gland, the inner gland cancer lesion and the nuter gland cancer had no difference. Conclusions： Transrectal contrast enhanced uhrasonography had important value in distinguishing the normal prostate and prostatic carcinoma, and is helpful in diagnosing early prostatic carcinoma.