MSCT阻塞指数与血气分析值的相关关系

Correlation of MSCT obstruction index and results of blood gas analysis

目的:探讨急性肺栓塞(APE)病人CT阻塞指数与血气分析值的相关关系。方法:收集39例经CT肺动脉造影(CT pulmonary angiography,CTPA)检查确诊为APE的病例,既往无心肺疾病史。10例正常人作为对照组。CT所采集图像通过容积重建(VR)、多平面重建(MPR)、曲面重建(CPR)等后处理技术处理,观察肺动脉栓塞支数及程度,使用Qanadli评分方法进行CT阻塞指数计算。测量病人入院后首次血气分析值包括氧分压(PaO2)、二氧化碳分压(PaCO2)、氧饱和度(SaO2)和P(A-a)O2值。结果:APE病人PaO2,PaCO2,SaO2均较对照组显著减低(P值分别为0.02,0.004,0.003)。APE组中CT阻塞指数与PaO2、PaCO2和SaO2均呈显著负相关(PaO2,r=-0.643,P<0.05;PaCO2,r=-0.771,P<0.05;SaO2,r=-0.718,P<0.05)。而CT阻塞指数与P(A-a)O2呈显著正相关(r=0.735,P<0.01)。结论:APE患者的CT阻塞指数与血气分析值具有显著相关关系,可作为评价APE较直观的有效指标。

Objective： To investigate the relationship between the pulmonary artery obstruction index with MSCT pulmonary angiography and results of blood gas analysis in patents with acute pulmonary embolism （APE）. Methods： Thirty-nine patients with proven pulmonary embolism by MSCT pulmonary angiography who were free of underlying cardiopulmonary disease before were included in this study. Ten volunteers were recruited in the control group. The severity of pulmonary embolism was assessed by the Qanadli＇s pulmonary, artery obstruction index using post-processing technology of MSCT workstation such as VR, MPR and CPR. We assessed the correlation of the MSCT obstruction index with the values of PaO2, PaCO2, SaO2 and P（A-a）O2. Results： The values of PaO2, PaCO2, SaO2 were significantly lower（P=0.02, 0.004, 0.003 respectively） in the patients of APE than those in control group. A significant correlation was observed between the obstruction index and resuits of blood gas anatysis[PaO2, r=-0.643, P〈0.05; PaCO2, r=-0.771, P〈0.05; SaO2, r=-0.718, P〈0.05; P（A-a）O2, r=0.735, P〈 0.01]. Conclusion： The MSCT obstruction index is correlated to the parameters of blood gas analysis significantly in patients with APE. It can be an effective index to evaluate the severity of APE.