骨折患者血小板相关参数检测的临床意义

The Clinical Significance of the Detection of the Platelet Parameter in Fractured Patients

目的：探讨骨折患者血小板相关参数的变化及与术后愈合的相关关系。方法：定期检测126例骨折患者血小板计数（PLT）、血小板平均体积（MPV）、血小板分布宽度（PDW）、大血小板比率（P-LCR）四项血小板参数。结果：126例骨折患者中受伤后4周内至少有一次PLT≥350×109/L（A组）占41.3%,PLT〈350×109/L而最高值与最小值相差≥50%（B组）占31.7%,PLT〈350×109/L而最高值与最小值相差〈50%（C组）占27.0%。三组平均治愈时间分别为34、25、28 d,A组与B组的治愈时间存在显著性差别（P〈0.05）。骨折患者在受伤后第1周内与受伤后第2~4周的PLT、MPV、PDW、P-LCR结果,受伤后第2~3周与受伤后第4周的PLT结果,受伤后24 h内与受伤后2~7 d（第1周）的MPV、P-LCR结果的差别均有显著性意义（P〈0.05）。结论：骨折患者受伤后血小板相关参数均不同程度的反应性增加,提示血小板在创伤恢复中起着重要作用。

Objective：To investigate the relationship between the variation of the platelet（PLT）parameters in catalysis subject and their healing after operation.Methods：Four PLT parameters of 126 fractured patients,such as PLT,MPV,PDW and P-LCR were regularly examined.Results：In the 126 fractured patients,after four weeks,they had at least one examination of the following：PLT≥350×109/L（group A,41.3%）,and PLT〈350×109/L but the variation between the highest and the lowest was≥50%（group B,31.7%）,PLT〈350×109/L but the variation between the highest and the lowest was〈50%（group C,27.0%）.The average curing time of the three groups were 34,25 and 28 days respectively.There was significant difference in the curing time between group A and group B（P〈0.05）.There was noticeable significance（P〈0.05）between the results of PLT,MPV,PDW,P-LCR in fractured patients after injury in the first week and 2～4 weeks,the results of PLT after injury in 2～3 weeks and the fourth week,the results of MPV,P-LCR after injury in 24 hours and 2～7 days（the first week）.Conclusion：The PLT parameters of fractured patients are all reactively increased in various degrees after the injury and the results indicate that the PLT plays an important role in the recovery of wounds.