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门控心肌灌注显像诊断冠心病的临床价值 被引量:4

The Value of 99mTc-MIBI Gated SPECT in Detection of Coronary Artery Disease
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摘要 目的:探讨腺苷负荷99mTc-MIBI门控心肌灌注显像(G-MPI)后室壁运动和增厚率异常对冠心病的诊断价值。方法:对91例确诊或临床疑诊为冠心病患者行静息-腺苷负荷99mTc-MIBI G-MPI和非门控心肌灌注显像(MPI),两周内行冠状动脉造影(CAG),对其结果进行对比分析。结果:MPI诊断冠心病的灵敏度为85.3%,特异性为73.9%,G-MPI诊断冠心病灵敏度为92.6%,特异性为87.0%,结合腺苷负荷后局部室壁运动和增厚率评分可提高G-MPI诊断冠心病的灵敏度和特异性。结论:静息-腺苷负荷99mTc-MIBI G-MPI对冠心病的诊断有较高的灵敏度和特异性。 Objective:To study the value of regional wall motion and thickening abnormalities on adenosine 99mTc-MIBI gated SPECT(G-MPI) in detection of coronary artery disease.Methods:Ninety-one patients underwent the rest-adenosine stress 99mTc-MIBI gated SPECT(G-MPI) and non-gated SPECT(MPI),all of the cases accepted coronary angiography in two weeks,and the results were compared.Results: The sensitivity of MPI and G-MPI were 85.3% and 92.6% respectively,and the specificity of MPI and G-MPI were 73.9% and 87.0% respectively.The abnormalities of regional wall and thickening had a high positive predictive value in detection of coronary artery disease,which enhanced the sensitivity and specificity of G-MPI in detection of coronary disease.Conclusion: Rest-adenosine stress 99mTc-MIBI G-MPI has high specificity in detection of coronary artery disease.Combination with regional wall motion and thickening enhances its sensitivity and specificity in detection of coronary artery disease.
作者 李艳梅 李娟
出处 《华西医学》 CAS 2008年第4期824-826,共3页 West China Medical Journal
基金 宁夏自治区自然科学基金(NZ0796)
关键词 冠心病 门控心肌灌注显像 腺苷 心肌缺血 coronary artery disease G-MPI adenosine myocardial ischemia
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参考文献10

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二级参考文献18

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