摘要
目的：建立唇炎颗粒质量控制标准.方法：用薄层色谱法检测制剂中的生地、当归、防风和丹参,并运用高效液相色谱法测定梓醇的含量.结果：定性鉴别分离度好,专属性强;梓醇进样量为0.402～3.618μg时与峰面积呈良好线性关系（r=0.9997,n=5）,测得制剂中的梓醇含量稳定.结论：所建立的方法可靠、准确、专属性强,可用于该制剂的质量控制.
AIM： To establish a method for quality control of Chunyan granule. METHODS： Radix Rehmanniae, Radix Angelicae sinensis, Radix Saposhnikoviae, Radix Salviae mihiorrhizae were identified by thin layer chromatography（TLC）. Catalpol content was determined by high performance liquid chromatography （ HPLC ）. RESULTS ： The characteristic identification by TLC was distinct and highly specific. Catalpol showed a good hner relationship with area at a range of 0. 402 - 3. 618 μg （ r = 0.9997, n = 5 ）. Catalpol content of the granule was steady. CONCLUSION： The method is reliable, accurate and specific. It can be used for quality control of Chunyan granule.
出处
《第四军医大学学报》
CAS
北大核心
2008年第21期1966-1969,共4页
Journal of the Fourth Military Medical University
基金
军队医药卫生科研基金(06M269)
