泰勒宁治疗肝癌TACE术后疼痛300例的疗效评价

The therapeutic effect appraise of Tylox treating the ache after TACE technique for 300 hepatic carcinoma cases

目的:探讨氨酚羟考酮片用于肝癌行经导管肝动脉化疗栓塞术(TACE)后疼痛的止痛效果。方法:2007年1月-2008年7月,我院应用泰勒宁片治疗TACE术后疼痛患者300例,观察泰勒宁片治疗TACE术后疼痛的疗效。结果:中度疼痛组缓解显效率为88.2%,有效率为11.8%,其中单次给药的总有效率为40.1%,重度疼痛组显效率为57.1%,有效率为27.0%。本研究总有效率为96.7%,没有发现与泰勒宁有关的呼吸抑制、药物过敏、精神依赖等严重不良反应。结论:泰勒宁片用于治疗肝癌行TACE术后疼痛疗效肯定,有关的不良反应少见,为临床治疗肝癌TACE术后疼痛提供了一个良好的选择。

Objective： To assess the efficacy of oxycodone and acetaminophen tablets（Tylox） for the treatment of the ache after transeatheter arterial chemoembolization （TACE）. Methods： From January 2007 to July 2008,300 hepatic carcinoma cases were given Tylox for the ache after TACE, improvements in pain and adverse reaction were observed. Results： Excellence rate and effective power were 88.2% and 11.8% respectively in mod- erate pain and serious pain were 57.1% and 27.0% ,total effective rate was 40.1% in single dose group of moderate pain. Total effective rate was 96.7% on this study, and no patient had serious adverse reaction such as respiratory depression,drug hypersensitivity, psychological dependence,et al. Conclusion： Tylox is definitely effective on the pain caused by TACE, and with a few adverse reaction, which is a satisfactory choice in this field.