摘要
目的:探讨氨酚羟考酮片用于肝癌行经导管肝动脉化疗栓塞术(TACE)后疼痛的止痛效果。方法:2007年1月-2008年7月,我院应用泰勒宁片治疗TACE术后疼痛患者300例,观察泰勒宁片治疗TACE术后疼痛的疗效。结果:中度疼痛组缓解显效率为88.2%,有效率为11.8%,其中单次给药的总有效率为40.1%,重度疼痛组显效率为57.1%,有效率为27.0%。本研究总有效率为96.7%,没有发现与泰勒宁有关的呼吸抑制、药物过敏、精神依赖等严重不良反应。结论:泰勒宁片用于治疗肝癌行TACE术后疼痛疗效肯定,有关的不良反应少见,为临床治疗肝癌TACE术后疼痛提供了一个良好的选择。
Objective: To assess the efficacy of oxycodone and acetaminophen tablets(Tylox) for the treatment of the ache after transeatheter arterial chemoembolization (TACE). Methods: From January 2007 to July 2008,300 hepatic carcinoma cases were given Tylox for the ache after TACE, improvements in pain and adverse reaction were observed. Results: Excellence rate and effective power were 88.2% and 11.8% respectively in mod- erate pain and serious pain were 57.1% and 27.0% ,total effective rate was 40.1% in single dose group of moderate pain. Total effective rate was 96.7% on this study, and no patient had serious adverse reaction such as respiratory depression,drug hypersensitivity, psychological dependence,et al. Conclusion: Tylox is definitely effective on the pain caused by TACE, and with a few adverse reaction, which is a satisfactory choice in this field.
出处
《中国新药杂志》
CAS
CSCD
北大核心
2008年第20期1802-1804,共3页
Chinese Journal of New Drugs
关键词
泰勒宁
疼痛
疗效
肝癌
肝动脉化疗栓塞术
tylox
ache
efficacy
hepatic carcinoma
transcatheter arterial chemoembolization