真皮下切割除皱术的实验与临床应用研究

The reconstruction of skin structure for aging skin

根据植皮后不产生皱纹的原理，进行真皮下分离和切割，以增加真皮组织中胶原蛋白的含量，修复断裂的胶原。实验结果表明，术后１５天，经切割的皮肤面积缩小３０％左右（Ｐ＜０．０１），表皮层增厚，表皮真皮交界处表皮钉加深，乳突增高，皮面平坦，无凹凸不平。临床应用后，可明显减少外眦鱼尾纹、鼻唇沟皱纹，对消除细小皱纹具有良好疗效。

On the basis of the character of degerneration and damage of aging skin ,the structure of aging skin was repaired and reconstructed in order to increase the content of collagen protein and replace the degerneration collagen in dermis. The animal experiment showed that the area of the treated was reduced by nearly 30 % (P<0.01).The epidermis layer became thicker and the demis layer contained more fibroblasts and melting collagen than before. 7 patients were treated with this method and their Crows feet deformity and wrinkles near nasolabial groove almost disappeared after the operation.