西安地区儿童败血症主要病原菌分析

目的:研究西安地区儿童败血症主要病原菌。方法:用BacT/ALERT3D全自动血培养仪对200例儿童血培养阳性检查结果进行分析。结果:①儿童败血症主要病原菌为革兰阳性菌(82.6%);其次为革兰阴性菌(12.0%);真菌感染仅为3.0%。②革兰阳性菌感染的败血症以葡萄球菌为主,占革兰阳性菌感染败血症的95.0%,其中以金葡和表葡最为常见。对青霉素耐药率为90%以上,对万古霉素耐药率为0。③革兰阴性菌感染的败血症以肠杆菌科为主(51.2%),ESBLs阳性率为40.4%;革兰阴性非发酵菌占革兰阴性菌感染败血症的47.0%,以铜绿假单胞菌常见。结论:细菌的耐药性已成为临床治疗的棘手问题,因此应根据药敏实验结果合理用药,减少细菌耐药的发生。

OBJECTIVE：Research on primary pathogenic bacteria of children septicemia in Xi＇an. METHODS： Tested 200 cases of children septicemia by BacT/A- LERT3D automatic blood culture analyzer. RESULTS：①The main pathogenic bacteria in children septicemia was gram - positive （ G ＋ ） bacteria, 82.6% ; next was gram - negative （ G - ） bacteria, 12. 0% ; fungous only accounted for 3.0% of infections.② 95.0% of septicemia - causing G ＋ bacteria was Staphylococcus, among which Staphylococcus aureus and Staphylococcus epidermidis were most common. 90% of pathogenic bacteria were resistive to penicillin and all of them were sensitive to vancomycin. ③ The main septicemia- causing G- bacteria was enteric bacilli, 51.2%, and 40. 4% of that was ESBLs positive. 47. 0% of septice- mia - causing G - bacteria was Nonferment- ers and Pseudomonas aeruginosa was most common. CONCLUSION： The drug resistance of pathogenic bacteria had become an intractable problem in clinical medicine. Appropriate medication based on drug - sensitivity results should put into administration to reduce the rate of drug resistance.