80例睡眠呼吸暂停综合征患者中医证候分析

Study on the TCM syndromes of 80 Patients with Sleep Apnea Syndrome

目的对睡眠呼吸暂停综合征(SAS)患者进行中医证候规律的临床研究,为中医辨证治疗提供依据。方法采用横断面调查问卷方法对经过多导睡眠监测确诊的SAS患者,进行中医证候问卷调查,计算其症状频数,分析SAS的中医证候特征和分型。结果痰证患者最为多见,共计61例次(76.25%);其次为瘀血证34例次(42.50%);舌色以淡白和暗红较为多见,舌体以胖带齿痕和舌腹经脉瘀曲较为多见,舌苔以腻苔较为多见。轻度SAS中痰证38例次,占90.5%,提示轻度患者以痰证为主;中重度患者以体虚夹瘀为主。结论SAS证候分型多为虚实夹杂,以痰证和血瘀证多见,轻度以痰证为主,中度以痰瘀互结为主,重度以血瘀证为主。

Objective To study the laws of TCM syndromes of sleep apnea syndrome （SAS） to provide evidence for treatment. Methods A survey-based, cross-sectional descriptive study was carried out on 80 patients with SAS diagnosed by overnight polysomnography. The questionnaire contained sociodemographic and clinical items and evaluation for symptoms of TCM. Results Of 80 patients, phlegm-damp was the most common syndrome, 61 cases, 76.25%, followed by blood stasis, 34 cases, 42.50%. The tongue was pale and dark red, enlarged with tooth prints and curved veins, and with sticky coating. In mild cases, 38（90. 5%） were of phlegm-damp syndrome, indicating that the mild cases were mainly of phlegm-damp syndrome and the moderate and severe cases mainly of deficiency with stasis. Conclusion SAS is mainly of deficiency complicated with excess, phlegm-damp and blood stasis are common syndromes, the mild cases were mainly of phlegm-damp, the moderate cases mainly of combination of phlegm with stasis, and the severe cases mainly of stasis.