摘要
为了解已酰唑胺治疗中心性浆液性视网膜脉络膜病变的疗效，作者用乙酰唑胺治疗中心性浆液性视网膜脉络膜病变患者20例；另设对照组20例，观察治疗前后自觉症状、纠正视力、眼底改变、药物副作用，并随访6～8个月。结果：治疗组11人在1个半月内恢复，4人在2个月以上恢复。对照组2人在1月半内恢复，11人在2个月以上恢复。两组在1个月半内恢复率有显著差异（χ2＝7．55，P＜0．01）。治疗组与对照组患者的最终疗效及复发率则无显著差异。乙酰唑胺治疗期间未见严重药物副作用。认为口服乙酰口袋胺治疗中心性浆液性视网膜脉络膜病变能缩短病程，短期内改善自觉症状，恢复视力，但无法提高疗效及控制本病复发。
The authors reported the changes of subjective improvement, corrected visual acuity, ocularfundus and side effects on patients with central serous choroidoretinopathy who had been randomly assigned to receive either oral acetazolamide (20 cases, treatment group) or no acetazolamide (20 cases, control group ). The follow-up Period ranged from 6 to 8 months. The recoveryrates of the two groups within one and a half months were significantly different (P<0. 01).The results indicated that acetazolamide might shorten the clinical course of the disease, However,there were no differences in final effect and recurrence rate between two groups. No serious sideeffects of the drug were observed.
