辛伐他汀降脂疗效观察

目的探讨辛伐他汀的降脂效果。方法选择2006年7月～2007年5月我科收治的60例患者，给予辛伐他汀治疗，观察用药前后TC、TG、LDL—C和HDL-C的变化。结果治疗后患者TC、TG和LDL—C水平明显降低，而HDL-C水平提高，与治疗前比较差异有统计学意义（“P〈O.05”）；降低TC、TG和LCL-C总有效率分别为88.3％、61.7％和78．3％，升高HDL-C总有效率为66．7％。结论辛伐他汀的降脂效果值得肯定，有临床推广价值。

Objective To explore the effect of simvastatin to reduce serum lipid. Methods Select 60 patients that treated in our department from July 2006 to May 2007, who are treated with I simvastatin and observed the change ofTC, TG, LDL-C and HDL-C before and after treated. Results After treated, the level of TC, TG and LDL-C are obviously decreased, and the level of HDL-C is improved, the difference is statistical significant compared with before treated; the total effect rate of decreasing TC, TG and LCL-C is 88.3%, 61.7% and 78.3%, while the total effect rate of improving HCL-C is 66.7%. Conclusion Simvastatin has good effect to reduce serum lipid and can be widely used in clinic.