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血管内皮生长因子在妇科肿瘤中的研究进展 被引量:5

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摘要 血管内皮生长因子(VEGF)也称血管渗透因子,是一种重要的血管生成因子,主要由血管内皮细胞产生。它是近年来发现的特异的作用于血管内皮细胞的高效促有丝分裂因子,在刺激新血管发生与生长及维持血管壁的完整性和通透性方面均有重要意义。VEGF广泛见于肿瘤及非肿瘤的病理生理过程中,肿瘤组织的VEGF表达水平与其微血管密度及恶性程度呈正相关,并明显高于非肿瘤组织。这表明VEGF以促进血管形成的方式促进肿瘤生成,尤其在高度血管化肿瘤中。
出处 《当代医学》 2008年第11期11-12,共2页 Contemporary Medicine
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  • 2刘雄光,黄光武.血管内皮生长因子在头颈部肿瘤的表达及意义[J].山东大学耳鼻喉眼学报,2007,21(1):89-92. 被引量:3
  • 3曾瑄,王鹏,武莎斐,高洁,梁智勇,刘彤华.结直肠癌EGFR和HER2蛋白表达及其基因拷贝数分析[J].中华病理学杂志,2007,36(7):447-452. 被引量:8
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