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替诺福韦酯与拉米夫定和阿德福韦酯抗HBV疗效对比研究进展 被引量:2

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摘要 替诺福韦酯(TDF)是替诺福韦的前药,是一个新型的无环核苷(酸)类似物,临床研究显示其对HBV、合并HIV感染及拉米夫定耐药患者具有良好的抗病毒作用。而最新的研究也表明,TDF单独应用治疗CHB单一感染也有着较好的疗效和病毒抑制作用。由于TDF的抗HBV作用优于阿德福韦酯,耐药发生率低,且对大多数HBV耐药株有效,因此,TDF在HBV感染的治疗中具有广阔的应用前景。
出处 《实用肝脏病杂志》 CAS 2008年第6期429-432,共4页 Journal of Practical Hepatology
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