胰岛素泵在治疗Ⅱ型糖尿病患者中的作用

The Effect ofInsulin Pump in Ttreating Patients with Type 2 Diabetse

目的探讨应用胰岛素泵治疗Ⅱ型糖尿病的临床价值。方法将128例Ⅱ型糖尿病患者分为连续皮下注射胰岛素(continuous subcutaneous insulin infusion,CSⅡ,n=64)和每天多次皮下注射胰岛素(multiple subcutaneous insulin injection,MSⅡ,n=64)。CSⅡ组将短效胰岛素置于胰岛素泵内持续皮下注射,进餐前再按所需输入负荷量;MSⅡ组将短效胰岛素装入普通注射器内于每天三餐前及22:00皮下注射,治疗2周后对两组的疗效进行比较。结果2种方法均可使患者的血糖达标。CSⅡ组血糖达标所需时间为(6.4±1.2)d,MSⅡ组所需时间为(9.9±1.8)d;CSⅡ组血糖达标所需胰岛素用量为(36.1±7.3)U/d,MSⅡ组血糖达标所需胰岛用量为(42.7±6.9)U/d,CSⅡ组低血糖发生次数为0.04次/(d.人),MSⅡ组低血糖发生次数为0.08次/(d.人)。两组上述指标比较差异均有统计学意义,均为P<0.05。结论CSⅡ能更快速地控制Ⅱ型糖尿病患者的血糖,所需胰岛素用量较少,低血糖发生率较低。

Objective To explore the insulin pump in treating type 2. diabetes clinical value. Methods Divides into continuous subcutaneous insulin infusion （CS Ⅱ ,n=64） and each multiple subcutaneous insulin injection （MS Ⅱ ,n=64）128 examples type 2 diabetes. The CS Ⅱ group puts in the short effect insulin in the insulin pump to continue the hypodermic injection,before dining, presses again must input the load; The MS Ⅱ group loads short effect insulin in the ordinary injector before every 3 meals and 22：00 hypodermic injection. Treats 2 weekd later carries on the comparison to 2 groups of curative effects. Results 2 methods may cause patien＇s blood sugar to attain a designated standard. The CS U group blood sugar standards need （6.4±1.2） days,The MS Ⅱgroup institute need （9.9±1.8）days; The CS Ⅱ group blood sugar standards needs the insulin amount used for （36.1±7.3）U/d,The MS H group blood sugar standards needs the insulin amount used for （42.7±6.9）U/d, The CS Ⅱ group hypoglycemia has the number of times is 0.04 time/（Day.person）,The MS II group hypoglycemia has the number of time is 0.08 time/（Day.person）.2 groups of above target comparison difference have statistics significance, is P〈0.05. Conclusion CS Ⅱ can control type 2 diabete＇s blood sugar fast, uses few insulin, with low rate of the hypoglycemia.