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胰岛素联合二甲双胍治疗初发Ⅱ型糖尿病42例报告

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摘要 目的评价胰岛素联合二甲胍治疗初发Ⅱ型糖尿病的临床疗效。方法对42例新诊断Ⅱ型糖尿病患者进行为期4周的胰岛素联合二甲双胍强化治疗,观察治疗前后的空腹血糖(FPG)、餐后2h血糖(hPG)、糖化血红蛋白(HbAlc)、空腹胰岛素(Fins)、C肽(C-P)水平和胰岛素抵抗指数(Homa IR)。结果治疗后,患者的FPG、2 hPG、HbAlc均较治疗前明显下降(P<0.01),胰岛素抵抗指数较治疗前明显下降(P<0.01),Fins、C肽明显上升(P<0.05)。结论对初诊的Ⅱ型糖尿病患者采用胰岛素联合二甲双胍能够全面控制血糖,改善胰岛B细胞功能,减轻胰岛素抵抗。
作者 党建英
出处 《医学信息》 2008年第12期2269-2270,共2页 Journal of Medical Information
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