颈动脉粥样硬化斑块与中老年心脑血管病及相关因素分析

Analysis of correlation between carotid plaques and middle and old aged heart cerebrovascular disease

目的:探讨颈动脉粥样硬化斑块与中老年心脑血管病及相关因素的关系。方法:将455例住院患者予颈动脉超声检查,观察颈动脉粥样硬化斑块与性别、年龄、高血压病、糖尿病、冠心病、脑梗死、高尿酸血症、血脂的关系,又按年龄分成3组,分析组间各因素间关系。结果:年龄、高血压病、糖尿病、冠心病、脑梗死、高尿酸血症与斑块形成有显著关系(P<0.05)。中年期脑梗死、糖尿病与斑块有显著关系,老年前期糖尿病、高血压病、冠心病与斑块有显著关系,老年期高尿酸血症、高血压病、冠心病、脑梗死与斑块有显著关系。结论:年龄、高血压病、糖尿病、高尿酸血症是斑块形成的危险因素,斑块形成与冠心病、脑梗死密切相关。颈动脉超声检查简便、无创、重复性好,对在不同年龄段并有相关疾病及危险因素的中老年患者进行定期检查,及时发现早期斑块及性质判断,可以提供临床积极干预的依据,及时预防治疗临床心脑血管事件,临床应用价值高。

Objective：To investigate the correlation of carotid plaques with heart eerebrovascular disease and correlation factor in the middle and old aged.Methods：Carotid artery was evaluated in 455 patients in hospital. The relationship of carotid plaques with the sex, age,hypertension,diabetes,coronary disease,cerebral infaretion,hyperurieaemia,the blood lipid were analysed. These patients were also divided into 3 groups according to the age,each group of various factors related was analysed respectively.Results：There was significant correlation between carotid plaques and age,hypertension,diabetes,coronary disease,cerebral infaretion,hyperuricaemia （P〈O.OS）.There was significant correlation between cerebral infarction,diabetes in the middle-aged time.There was significant correlation between dia- betes,hypertension,coronary disease in the old age earlier period. There was significant correlation between hyperurieaemia,hyperten- sian,coronary disease,cerebral infarction in old stage.Conclusion：The age,hypertension,diabetes,hyperuricaemia was the hazard factors of carotid plaques. There is a close relationship between carotid plaques with the coronary disease and cerebral infarction. The carotid ultrasonography is simple,hurtless and repeatable. We need to carry on the periodic inspection to the middle and old aged patients in different ages who have related disease and hazard factor. To find carotid plaques and judge the nature in time can provide the basis of the clinical positive intervention,prevent and treat heart cerebrovascular disease.The clinical practice value is high.