甲基丙烯酰胺对氨基水杨酸功能单体的合成

Synthesis of a 4-methacrylamidosalicylic acid functional monomer

以甲基丙烯酸酐和对氨基水杨酸为原料,制得甲基丙烯酰胺对氨基水杨酸。所得产物结构采用IR和1H NMR进行表征。考察了反应温度、反应时间和原料配比对收率的影响。结果表明,最佳反应条件为:n(甲基丙烯酸酐)∶n(对氨基水杨酸)=0.559∶1,温度32℃,反应时间30h,在此条件下,产物收率在88.89%左右。

4-Methacrylamidosalicylic acid was synthesized from methacrylic anhydride and 4-aminosalicylic acid and the product was characterized by IR and ^1H NMR. The effects of reaction temperature, reaction time and proportion of the reactants were investigated. Product yield of 88.89% was obtained under the following condition ： n （ methacrylic anhydride） ： n （4-aminosalicylic acid） = 0. 559： 1, 32 ℃, reaction for 30 h.