摘要
以甲基丙烯酸酐和对氨基水杨酸为原料,制得甲基丙烯酰胺对氨基水杨酸。所得产物结构采用IR和1H NMR进行表征。考察了反应温度、反应时间和原料配比对收率的影响。结果表明,最佳反应条件为:n(甲基丙烯酸酐)∶n(对氨基水杨酸)=0.559∶1,温度32℃,反应时间30h,在此条件下,产物收率在88.89%左右。
4-Methacrylamidosalicylic acid was synthesized from methacrylic anhydride and 4-aminosalicylic acid and the product was characterized by IR and ^1H NMR. The effects of reaction temperature, reaction time and proportion of the reactants were investigated. Product yield of 88.89% was obtained under the following condition : n ( methacrylic anhydride) : n (4-aminosalicylic acid) = 0. 559: 1, 32 ℃, reaction for 30 h.
出处
《工业催化》
CAS
2008年第11期58-60,共3页
Industrial Catalysis
基金
国家重点基础研究发展计划(973计划)(2005CB623702)