乙型肝炎病毒经手术传播的防护方法

Protection Method of Hepatitis B Virus Transmission through Operation

目的为控制经手术传播乙型肝炎病毒(HBV),提供防护方法。方法比较以乙肝e抗原(HBeAg)为指标的手术中HBV传染源监控方法和西方国家现有HBV经手术传播防护方法的差别。结果HBV经单层手套传播的感染阈值为105ID/ml,经双层手套传播的感染阈值为106ID/ml。双层手套只能使病毒数量减少1个对数级。67.74%HBeAg阳性者达到双层手套的感染阈值,最大传染性可达103ID/ml。83.88%HBeAg阳性者的病毒浓度达到单层手套感染阈值,80.65%在乙肝疫苗有效免疫者的防护范围之内,剩余3.23%超过了这种防护能力。结论以HBeAg为指标的手术中HBV传染源监控方法和西方国家现有HBV经手术传播的防护方法都属于零危险性防护标准,以前者更具有优越之处。

[ Objective] To provide protection method of hepatitis B virus （HBV） transmission through Operation. [ Methods] To compare the differences between the measures which use HBeAg as index to supervise and control infection during operation and the current protection method against HBV transmission through operation in the western countries. [ Results ] HBV infection threshold value of single layer gloves is 10.5 ID/ml , and that of double layer gloves is 10.6 ID/ml. Double layer gloves can only reduce one logarithms class of virus. 67.74% HBeAg positive patients reach the HBV infective threshold value of double layer gloves, the maximum infectivity reached 10.3 ID/ml. 83.88% HBeAg positive patients reach the HBV infective threshold value of single layer gloves, 80.65% were in the effective prevention of HBV vaccine responders, the remaining 3.23% exceeded the prevention. [ Conclusion] The measures, which use HBeAg as index to supervise and control infection during operation and the current protection method against HBV transmission through operation in the western countries are both zero risk protection standards, the former is more advantageous.