血清C-反应蛋白对急性一氧化碳中毒患者预后的影响

Change of serum C-reactive protein levels and its influence on prognosis of patients with acute CO poisoning

目的探讨急性一氧化碳中毒(ACOP)患者血清C-反应蛋白(CRP)的水平变化及其对预后的影响。方法对49例ACOP患者血清CRP水平进行测定,并根据中毒的程度及预后进行分组比较分析。结果①中毒第2dACOP患者血清CRP水平重度中毒组和中度中毒组均高于健康对照组(P<0.01),轻度中毒组与健康对照组比较差异无统计学意义(P>0.05)。②中毒第2dACOP患者血清CRP水平与预后严重程度显著相关。结论ACOP患者血清CRP水平与中毒的程度及预后相关,可作为ACOP患者诊疗的重要参考指标之一。

Objective To explore the change of serum C-reactive protein（CRP）levels in patients with a- cute CO poisoning （ACOP） and its influence on the prognosis. Methods The serum CRP levels in 49 patients with ACOP were measured,and the relative analysis between the serum CRP level and the prognos is were performed. Results ①the CRP levels in moderate and severe poisoning groups were higher than that in the healthy contrast group on the second day after poisoning,with statistical difference （P〈0.01）; howere there was no statistical difference between mild poining group and healthy contrast group （P〉0.05）. ②serum CRP levels in patients with ACOP on the second day after poisoning were related well to prognosis. Conclusion Serum CRP levels in patients with ACOP are related well to poisoning degrees and prognosis,it can be used as an indicative index for diagnosing and treating patients with ACOP .