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单药多西他赛周方案治疗老年晚期非小细胞肺癌65例

Weekly Docetaxel in the Treatment of 65 Elderly Patients with Advanced Non-small Cell Lung Carcinoma
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摘要 [目的]评价单药多西他赛周方案治疗老年晚期非小细胞肺癌(NSCLC)的临床疗效和毒副作用。[方法]2000年10月~2006年3月收治的65例年龄63~82岁老年晚期NSCLC患者应用单药多西他赛周方案化疗,剂量为35mg/(m2·w),连用3周,休息1周,治疗有效者最多接受16周治疗或至疾病进展。[结果]65例患者共接受503周多西他赛化疗,PR19例,有效率29.2%;稳定26例,占40%。1年生存率32.4%,2年生存率8.6%。主要毒副作用轻微。[结论]单药多西他赛周方案治疗老年晚期NSCLC耐受性良好,安全有效。
出处 《肿瘤学杂志》 CAS 2008年第11期890-891,共2页 Journal of Chinese Oncology
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  • 1Earle CC, Tsai JS, Gelber RD, et al. Effectiveness of chemotherapy for advanced lung cancer in the elderly: instrumental variable and propensity analysis[J]. J Clin Oncol, 2001, 19(4):1064-1070.
  • 2Lilenbaum R,Herndon J, Marcy L, et al. Single-agent(SA) versus combination chemotherapy (CC) in advanced nonsmall cell lung cancer (NSCLC): a CALGB randomized trial of efficacy,quality of life (QOL),and cost-effectiveness[R]. Proc Am Soc Clin Oncol, 2002, 21:2(abstr).
  • 3Camps C, Massuti B, Jimenez AM, et al. Two second-line docetaxel dose-schedules in advanced non-small cell lung cancer (NSCLC):a Spanish Lung Cancer Group (SLCG) phase Ⅲ trial[J]. Lung Cancer, 2003, 41(Suppl 2):S5.
  • 4Schuette W, Nagel S, Serke M, et al. Second-line chemotherapy for advanced non-small cell lung cancer (NSCLC) with weekly versus three-weekly docetaxel: results of a randomized phase Ⅲ study [R]. Proc Am Soc Clin Oncol, 2004, 23: 7036(abstr).
  • 5Hainsworth JD, Burris HA, Litchy S, et al. Weekly docetaxel in the treatment of elderly patients with advanced nonsmall cell lung carcinoma. A Minnie Pearl Cancer Research Network Phase Ⅱ Trial [J]. Cancer, 2000,89(2): 328-333.
  • 6Lilenbaum R,Rubin M,Samuel J,et al. A randomized phase Ⅱ trial of two schedules of docetaxel in elderly or poor performance status patients with advanced non-small cell lung cancer[J].J Thorac Oncol, 2007, 2(4):306-311.
  • 7谢晓冬,郑振东,屈淑贤,刘大为,刘永叶,张冠中,朴瑛,刘艳梅,单学健.单药多西他赛治疗老年晚期非小细胞肺癌每周方案与每三周方案的疗效及毒性比较[J].中华肿瘤防治杂志,2008,15(1):65-67. 被引量:10
  • 8张兰凤,张岚,胡茜.多西他赛每周方案二线治疗老年晚期非小细胞肺癌的临床观察[J].实用癌症杂志,2008,23(3):301-302. 被引量:11

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