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颅脑损伤患者血清热休克蛋白70水平的变化 被引量:3

The change of serum heat shock protein 70 in patients with head injury
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摘要 目的 探讨颅脑损伤患者不同时期血清中热休克蛋白70(Hsp70)水平的变化。方法用酶联免疫吸附试验(ELISA)检测颅脑损伤患者伤后1~6h、24~36h、60~90h血清Hsp70浓度并与其他创伤组及健康对照组进行比较。结果颅脑损伤患者1~6h、24~36h血清Hsp70浓度显著高于其他创伤组和健康对照组,60~90h显著高于对照组。结论血清Hsp70浓度有可能作为颅脑损伤早期诊断的参考指标。 Objective To investigate the ehange of heat shoek protein 70 ( Hsp 70) of head injuried patients in different periods after injury. Methods t-6h,24-36h,60-90h after injury the serum levels of Hsp70 in head injuried patients was measured by enzyme-linked immunosorbent assay and compared with other injury patient group and control group. Results The serum levels of Hsp70 in head injuried patients with 1-6h, 24-36h after injury were significantly higher than the eontrol group and the other injury patients group , and after 60-90 h the levels of Hsp 70 were significantly higher than the eontrol group. Conclusions Serum Hsp70 concentration may be used as an earlier diagnostic index in patients with head injury.
出处 《检验医学》 CAS 北大核心 2008年第6期664-665,共2页 Laboratory Medicine
基金 湖南省卫生厅基金资助项目(B2006-185)
关键词 热休克蛋白70 颅脑创伤 诊断 Heat shoek protein 70 Head injury Diagnosis
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