泛素-蛋白酶体途径降解蛋白质的机制及其组成成分被引量：1

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摘要泛素-蛋白酶体途径是降解细胞内蛋白质的主要途径。大致经过两个连续的过程:泛素和蛋白质底物进行连接,在底物的一端形成一段多聚泛素链:此多聚泛素链作为识别信号,26S蛋白酶体复合物对其识别并降解蛋白质。整个降解过程是消耗ATP的过程。本文对泛素-蛋白酶体途径降解蛋白质的机制作一综述。

作者俞赞临张洁于嘉屏

机构地区上海交通大学医学院附属仁济医院检验科

出处《国际检验医学杂志》 CAS 2008年第11期1017-1018,共2页 International Journal of Laboratory Medicine

关键词泛素蛋白信号转导

参考文献9

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国际检验医学杂志

2008年第11期

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