摘要
目的评价厄贝沙坦/氢氯噻嗪治疗原发性高血压的疗效及对左心功能的影响。方法50例原发性高血压患者均服用厄贝沙坦/氢氯噻嗪片1片,1次/d,观察服药前后血压、左心功能、血尿酸、电解质等指标变化及不良反应。结果患者血压明显下降(P<0.05),左心舒张功能及心脏整体功能得到改善,血生化指标无明显变化,无不良反应。结论厄贝沙坦/氢氯噻嗪片是治疗原发性高血压的有效药物,疗效好,不良反应少,患者依从性好。
Objective It is to evaluate the curative effect of Irbesartan and hydrochlorothiazide on primary hypertension and left ventricular function. Methods 50 cases of patients with primary hypertension were given one tablet of Irbesartan and hydrochlorothiazide once every day. The changes of indexes such as lood pressure, left ventricular function, serum uric acid and electrolyte and adverse reactions were observed before and after treatment. Results Blood pressure was brought down obviously(P〈 0.05) in the patients, left ventricular diastolic function and the whole function of heart were improved( P 〈 0. 05 ). There was no obvious change of blood biochemical indicators (P 〉 0.05) and rare adverse reaction. Conclusion Irhesartan and hydrochlorothiazide tablet is an effective medicine for primary hypertension, with good effect and compliance, less side effect.
出处
《现代中西医结合杂志》
CAS
2008年第34期5262-5263,5266,共3页
Modern Journal of Integrated Traditional Chinese and Western Medicine
关键词
厄贝沙坦/氢氯噻嗪
高血压
超声心动图
Irbesartan and hydrochlorothiazide
hypertension
echocardiogram