摘要
利用体外培养的胶质瘤细胞株及裸小鼠移植瘤模型,研究了巯基修饰剂丁胱亚磺酰亚胺(BSO)对其谷胱甘肽(GSH)含量的影响。结果表明:无论是离体还是整体用药,BSO均能降低胶质瘤细胞的GSH含量。
The effects of thiol modifier BSO on glioma cells were studied in the cultured gliomacells line and glioma bearing nudemouse. The results showed that BSO depleted intracellularGSH contents of glioma cells in vitro and in vivo.
出处
《临床神经科学》
1997年第4期187-190,共4页
Chinese Journal of Clinical Neurosciences