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胰岛素对卵巢颗粒细胞的作用 被引量:11

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摘要 卵泡生长和排卵需要颗粒细胞的正常增殖和功能表达,胰岛素是促进颗粒细胞增殖和发挥生理功能的重要因子,通过多条信号途径与其他因子相互作用,精密地调节颗粒细胞增殖、物质代谢、合成甾体激素。多囊卵巢综合征(PCOS)患者高胰岛素血症和胰岛素抵抗导致颗粒细胞增殖抑制、功能失调,抑制卵泡的正常生长和排卵。
出处 《生殖与避孕》 CAS CSCD 北大核心 2008年第11期677-680,共4页 Reproduction and Contraception
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参考文献21

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二级参考文献50

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