妊娠晚期妇女超声骨密度测定及结果分析

Analysis of ultrasound bone mineral density in late trimester of pregnancy

目的:了解妊娠晚期妇女的超声骨密度状况,为确立骨量减少和骨质疏松症是晚期妊娠并发症之一提供依据。方法:选择147例正常妊娠晚期妇女为检测对象,用定量超声骨密度仪(QUS)测定受检者足跟部骨密度(BMD)值,随机选择200例正常健康非妊娠妇女作为对照组,并以孕周分为3组(Ⅰ组28～31周,Ⅱ组32～35周,Ⅲ组36～足月)进行组间对比研究。结果:妊娠晚期妇女BMD值较对照组明显下降,Ⅱ组、Ⅲ组和Ⅰ组BMD值比较均明显降低,Ⅱ组和Ⅲ组比较差异无显著性。孕周与BMD值呈负相关性(r=-0.208,P<0.01),差异有显著性意义。结论:运用QUS测定晚孕BMD值,操作简便、安全,无创伤性,无辐射性,可客观评估妊娠晚期妇女的超声骨密度状况。

Objective： To find out the BMD status and establish the normal reference value of BMD of women in late trimester of pregnancy for providing scientific foundation for osteoporosis diagnosis and prevention. Methods： BMD for calcaneus＇s in 147 pregnant women who lived in Shenzhen was measured with QUS made in USA, they were divided into three groups according to gestational weeks , Ⅰ group pregnant between 28 - 31weeks,Ⅱ group pregnant between 32 -35weeks, ill group pregnant between 36 weeks - pregnancy at term, at the same time select 200 healthy young women as control group. Results： The BMD showed a decreasing tendency with increasing gestational weeks. There were significant difference between Ⅰ group and other groups, no significant difference between Ⅱ and Ⅲ group. Pearson correlation analysis showed a negatively correlation between the gestational weeks and BMD. Conclusion： Measurement of bone mineral density in pregnant women using ultrasonic bone densitometry is an approach which is not only easy and simple to perform , but also safe, noninvasive, and non - radioactive. With this method, it is possible to objective evaluate the BMD status of women in late trimester of pregnancy.