联合检测低密度脂蛋白和C反应蛋白在不同类型冠心病中的临床价值

Value of integrated detection of low-density lipoprotein and C-reactive protein in patients with diferent types of coronary heart disease

目的通过检测低密度脂蛋白(LDL-C)和C反应蛋白(CRP)在不同类型冠心病中的浓度,探讨LDL-C和CRP与稳定型心绞痛(SAP)、不稳定型心绞痛(UAP)及急性心肌梗死(AMI)的关系。方法入选冠心病患者92例,分为三组,SAP组36例;UAP组30例;AMI组26例;对照组26例。同时测定LDL-C和CRP浓度。结果①冠心病组LDL-C显著高于对照组;②AMI组、UAP组、SAP组CRP显著高于对照组,AMI组、UAP组CRP高于SAP组;③LDL-C未达标组CRP高于LDL-C达标组。结论联合检测LDL-C和CRP的水平可以判断冠心病的严重程度,对冠心病的诊断和治疗均有重要的参考价值。

Objective To investigate the possible relation between the levels of low-density lipoprotein （LDL-C） and C-reactive protein（CRP） in patients with diferent types of coronary heart disease. Methods The levels of LDL-C and CRP were measured and compared in 92 subjects included 36 with stable angina pectoris （SAP） ,30 with unstable angina pectoris（UAP） ,26 with acute myocardial infarction（AMI） and 26 control subjects to evaluate the relationship between LDL-C and CRP. Results ①The level of LDL-C in patients with CHD was significantly higher than those in the control subjects. ②The levels of CRP in patients with CHD, including SAP. UAP and AMI,were significantly higher than those in the control subjects, but the of CRP in patients with UAP and AMI were higher than those in SAP.③The level of CRP in patients with the level of LDL- C target met were higher than those in patients with the level of LDL-C target not met. Conclusion Joint detection of LDL-C and CRP may be helpful to assessing danger degree of coronary heart disease.