静脉内支撑治疗布加综合征临床研究

Clinical study of expandable venous stents for treatment of Budd Chiari syndrome

为了研究静脉内支撑治疗布加综合征的临床疗效，作者采用该方法对１０例布加综合征患者实施治疗，根据血管病变的部位和范围选择下腔静脉扩张内支撑、肝静脉扩张内支撑和肝内门体分流术。结果显示：术后患者临床症状明显改善，门静脉压力、下腔静脉压差显著下降，支撑血管血液流动正常，无操作并发症。经１～２１个月随访，出血复发１例，静脉造影示肝内分流道狭窄１例，下腔静脉再狭窄１例，均行再次介入治疗。作者认为，静脉内支撑治疗布加综合征具有创伤小、并发症少等特点，疗效显著，值得进一步推广应用和深入研究。

Expandable venous stents is a new method for treatment of Budd Chiari syndrome(BCS). Ten cases of BCS underwent expandable venous stents in inferior cava vein or/and in hepatic vein, or/and intrahepatic portosystemic shunt according to the location and the extent of lesion.Expandable venous stents were successful in all patients.No serious procedure related complications were observed. The symptoms and signs disappeared.Portal pressure and inferior cava vein pressure gradient reduced immediately after treatment.The blood in stents flowed quickly. During follow up of 1～21 months,rebleeding was observed in one case.The stenoses of intrahepatic shunts and inferior vena vein respectively occurred in two cases requiring repeat intervention.Therefore,expandable venous stent is safe and effective in patients with BCS,and will be of great value in wide application and further study.