生物钟与皮肤病

Biological clock and skin diseases

时钟基因是生物钟主要的分子基础,生物钟通过时钟基因的调节可在生物体内产生生物节律。近年来,生物钟与疾病发生间关系的研究已经成为热点,一些研究已经有力证明了生物节律紊乱与心血管疾病、癌症的发生发展存在着密切关系。近年来,很多学者注意到生物钟以及时钟基因的异常与皮肤病的发病相关,并做了初步研究,结果表明生物钟节律紊乱和皮肤病的发生发展存在一定联系。本文就针对生物钟研究的现状及生物钟与皮肤病的关系做一综述。

Clock genes are the primary molecular basis of the biological clock which can produce biological rhythm in the body by clock genes. For the past few years, it has already become focus to study the relationship between the clock genes and the development of disease. Close relation of circadian disorder to the development of cardiovascular disease and cancer has been powerfully evidenced by some studies. Recently, the correlation between the abnormal of biological clock and clock genes and skin diseases has been observed. And the result turned out to be a certain connection between circadian disorder and skin diseases. The current situation of the studies of clock genes and its relationship with skin diseases are thus reviewed in this paper.