宫颈恶性淋巴瘤5例临床病理分析

Primary malignant lymphoma of the uterine cervix clinicopathologic analysis of 5 cases

目的：探讨宫颈恶性淋巴瘤病理特征与治疗、预后关系。方法：应用光镜，电镜及免疫组化方法，回顾性分析５例宫颈原发恶性淋巴瘤的临床病理特点。结果：主要表现为阴道少量出血和子宫颈肥大或息肉。按ＡｎｎＡｒｂｏｒ分期大多数为ＩＥ期患者。４例来源于Ｂ细胞，属于粘膜相关性淋巴瘤；１例来源于Ｔ细胞。采取手术、化疗或放疗等方法综合治疗后，无１例复发或死亡。结论：宫颈原发恶性淋巴瘤大多数属于粘膜相关性淋巴瘤，预后较好。

Purpose To explore the relationship between the pathologic features of primary malignant lymphoma of the uterine cervix and the treatment effect and prognosis of the disorder. Methods A retrospective analysis on 5 cases of primary malignant lymphoma was carried out by immunohistochemical stain, light and electron microscopy observation. Results The patients typically presented with a little vaginal bleeding and enlarged cervix or cervical polyp. Most of them were classified as IE stage according to the Ann Arbor system. Four cases were mucosa associated lymphoma originated from B cell, the another originated from T cell. All patients were treated by surgery and chemotherapy and/or radiotherapy and no one relapsed or died. Conclusions Primary malignant lymphomas of uterine cervix are largely lymphomas of mucosa associated lymphoid tissues and have the better prognosis.