QCT应当在骨质疏松症的诊断、治疗中发挥更大的作用

QCT should give full play to diagnosis and treatment in osteoporosis

目的通过对现有骨密度测量方法优劣的比较,探讨骨密度测量的发展方向。方法回顾了过去20年中骨密度测量方法的发展与变迁。结果骨密度测量的发展史表明,骨密度测量是骨质疏松诊治的基础,然而,仅仅测量骨密度对于评估骨质疏松性骨折的风险性,对于判断疗效是远远不够的。"DXA检测骨密度准确度高、精确性好"是值得商榷的。DXA不能区分皮质骨与松质骨、其面密度测量的误差、增龄退变对测量的影响及对骨结构观察的限度在QCT测量中可以迎刃而解。结论应大力加强QCT检测骨密度的研究,最终使其取代DXA成为骨质疏松诊断的新标准。

Objective Inquire into development orientation for bone mineral density（BMD） measurement through comparing different bone mineral density measurement way. Methods Review the development and changes of the bone mineral density measurement way in last 20 years. Results The development history of bone mineral density measurement has made clear that the bone mineral density measurement is the basis for diagnosis and treatment of osteoporosis, however, merely measuring bone density for the assessment of the risk of osteoporosis fracture and the judgement of the curative effect is not enough. ＂DXA measuring BMD is with high accuracy and precision＂ is opened to question. Hard to distinguish between cortical and trabecular bone, the error of surface BMD measurement,the effect of aging degeneration for the measurement and the limits on observing bone structure in DXA measurement can be readily solved in QCT measurement. Conclusion QCT measurement should be vigorously strengthened and finally replace DXA to become the new standard diagnosis of osteoporosis.