D-核糖对大鼠负载游泳后胰岛素、去甲肾上腺素、肾上腺素的影响及其抗疲劳、抗缺氧能力研究

Effects of D-Ribose on Rat Plasma Insulin,Norepinephrine and Epinephrine after Load Swimming and Its Anti-fatigue and Anti-hypoxia Capabilities

通过灌服D-核糖,测定大鼠在负重游泳后血浆胰岛素、去甲肾上腺素和肾上腺素水平,研究D-核糖对运动后大鼠心脏及骨骼肌功能的恢复作用。灌服D-核糖,测定大鼠的抗疲劳游泳力竭时间与抗缺氧存活时间,探讨核糖的抗疲劳和抗缺氧能力。结果表明:运动后即刻核糖实验组胰岛素水平高于正常对照组和游泳对照组,恢复72h后,核糖组胰岛素水平均高于正常对照组;核糖实验组在运动后即刻去甲肾上腺素、肾上腺素水平高于游泳对照组,恢复72h后,核糖实验组肾上腺素水平低于游泳对照组和正常对照组;核糖组与对照组大鼠的抗疲劳游泳力竭时间、抗缺氧存活时间分别延长了50.21%和8.8%。结论:核糖可以调节激素水平,促进运动过程中的糖异生作用,对维持运动过程中血糖水平的稳定起重要作用,保护了心脑等重要器官的正常生理功能。补充核糖可以显著延长大鼠的抗疲劳游泳时间和缺氧状态下的存活时间。

In order to investigate the effects of D-ribose on the recovery of mt cardiac muscle and skeletal muscle function after load swimming and to discuss its anti-fatigue and anti-hypoxia capabilities, the concentrations of plasma insulin, norepinephrine and epinephrine, and the swimming time of rats subjected to fatigue and the survival time of rats subjected to hypoxia, were determined. The results indicated that after swimming the concentration of plasma insulin of D-ribose control groups （RCG） was higher than that of normal control group （NCG） and swimming control group （SCG）. After recovery of 72 h, the concentrations of plasma insulin of all D-ribose test group（RTG） are higher than that of NCG. The concentrations of norepinephrine and epinephrine of RTG are higher than those of SCG. After recovery of 72 h, the concentration of epinephrine of RTG is lower than that of NCG and SCG. The swimming time of rats subjected to fatigue and the survival time of rats subjected to hypoxia of RTG is prolonged by 50.21% and 8.8%, respectively. D-ribose can adjust the level of hormones, promote the process ofgluconeogen- esis and significantly prolong the swimming time of rats subjected to fatigue and the survival time of rats subjected to hypoxia. D-ribose plays an important role in maintaining the stabilization of blood sugar and protecting the normal physiological function of important organs.