放射损伤生物剂量估算技术研究

STUDIES ON THE DOSE ESTIMATION TECHNIQUES FOR RADIATION DAMAGE

本文围绕急性放射损伤的剂量估算问题,结合我院的实际情况,从生物剂量估算、电子自旋共振(ESR)剂量测量等方面,着重介绍我院所取得的主要科研成果和临床应用实例,从一定程度上反映了国内目前的研究进展。其中生物剂量估算技术包括染色体生物剂量计的不断完善和自动化分析、急性超大剂量照射的剂量估算技术、迁延照射及辐射远后效应的研究、淋巴细胞微核以及各种新的基于DNA靶分子辐射损伤的检测技术等;ESR测量技术介绍了我院目前的研究现状与应用情况,以及未来的发展趋势。

Around the dose estimation of radiation damage, major achievements in scientific research and clinical practice of the Academy of Military Medical Sciences are introduced in respect of biological dose estimation and ESR measure techniques. The techniques of radiation biological dose estimation include continuous perfection and automatic analysis of chromosome bio-dosimeter, the dose estimations for acute over-high dose exposure and protracted exposure, radiation late effects evaluation, lymphocyte micronucleus count and various new examination methods based on the damage of DNA molecule target. The status of study and application in ESR measurement is introduced and future development also prospected.