超声造影技术在肝脏局灶性病变诊治中的有效性及其应用进展

The Progress in the Effect and Application of Contrast-enhanced Ultrosonography in Diagnosing and Treating of Local Liver Diseases

传统彩色多普勒和能量多普勒超声对肝脏位置较深或体积较小的病灶缺乏良好的对比度,限制了临床应用。以微气泡超声对比剂为介质的超声造影技术提高了传统超声对血流的探测能力,并能动态观察组织的增强过程,有效反映病变的血流动力学变化,从而提高了超声对肝脏局灶性病变诊断的敏感性和特异性。超声造影技术在提高肝癌的检出率,鉴别肝脏良恶性局灶性病变方面显示出比常规超声和增强CT更多的优势,可以为肝肿瘤介入治疗后评估疗效提供新的途径。本文就目前应用超声造影技术诊断肝脏局灶性病变及其在评估治疗后的进展进行综述。

Conventional color Doppler and power Doppler ultrasonography are less effective in clinical application because of the lower contrast to deeper and shorter lesions in liver. The microbnhble contrast-enhanced uhrasouography can enhance the detection ability to blood flow, monitor the enhancement process of tissues dynamically and display the haemodyuamics changes effectively, which can raise the sensitivity and the specificity in diagnosing local liver diseases. The contrast-enhanced ultrasonography is more helpful in detecting hematocarcinoma and malignant lesions in liver, compared to conventional ultrasonography and enhanced computed tomography. This article reviewed the progress of the application of contrast-enhanced ultrasouography in diagnosing local liver diseases and assessing the effectiveness after treatment.