己酮可可碱治疗慢性肺源性心脏病急性加重期的临床观察

Clinical Observation on Pentoxifyllinein Treatment of Chronic Pulmonary Heart Disease at Acute Exacerbation

目的观察己酮可可碱对慢性肺源性心脏病急性加重期的疗效。方法84例慢性肺源性心脏病急性加重期患者随机分为治疗组和对照组。对照组给予常规治疗,治疗组在此基础上加用己酮可可碱静脉滴注。比较两组疗效及相关辅助检查指标。结果治疗组显效17例,有效24例,无效3例,对照组显效8例,有效23例,无效9例,差异有统计学意义(uc=5.69,P<0.05)。而且治疗组在降低肺动脉压、改善高黏滞血症及降低病死率等方面也优于对照组。结论己酮可可碱可用于缓解慢性肺源性心脏病急性加重期患者的病情。

Objective To explore the clinical effect of pentoxifylline in treatment of chronic pulmonary heart disease at acute exacerbation. Methods 84 patients with chronic pulmonary heart disease at acute exacerbation were divided into control group and treatment group. Both groups were treated with routine method,and the treatment group was added with pentoxifylline injection once day for successive 10 days. Then clinical effects and related auxiliary examination were checked up. Results After treatment,there is 17 cases with markedly effects ,24 with partially effects and 3 with no change in treatment group, and 8 cases with markedly effects ,23 with partially effects and 9 with no change in control group （ uc = 5.69 ,P 〈0.05 ）. Moreover, the treatment group was superior in decreasing pulmonary artery pressure, improving blood hyperviscosity syndrome and decreasing mortality than conventional treatment did. Conclusion Pentoxifylline injection has satisfactory therapeutic effect in treatment of chronic pulmonary heart disease at acute exacerbation.