摘要
目的探讨小剂量肝素治疗急性白血病前弥漫性血管内凝血(pre-DIC)的疗效及其安全性。方法急性白血病前DIC46例,随机分成2组,小剂量治疗组23例(A组),常规治疗组23例(B组),比较两组疗效。结果A组转化为DIC的患者少于B组(P<0.05)。D-二聚体转阴A组高于B组(P<0.05)。结论小剂量肝素治疗急性白血病Pre-DIC能有效阻止其向DIC发展,且具有良好安全性。
Objective To investigate curative effect and security of low-dose heparin treating predisseminated intravascular coagulation of acute leukemia.Method Forty-six cases with pre-disseminated intravascular coagulation of acute leukemia were randomly divided into low-dose treatment group （ Group A,23 eases） ,and conventional treatment group （ Group B,23 cases）. Results The numbers of patients developing into DIC were lower in Group A than those in Group B （ P 〈 0.05 ） , while the rate of D-dimefide darkening was higher in Group A than that in Group B （ P 〈 0.05 ）. Conclusion low-dose heparin can effectively prevent the occurrence of DIC,and has a good safety.
出处
《医学综述》
2008年第23期3666-3667,共2页
Medical Recapitulate
关键词
急性白血病
肝素
弥漫性血管内凝血
Acute leukemia
Heparin
Disseminated intravaseular coagulation
