促性腺激素释放激素Ⅱ及其受体与生殖
摘要
促性腺激素（Gn）释放激素（GnRH）通过刺激脑垂体释放黄体生成素（LH）和卵泡刺激素（FSH），对生殖系统起到中枢调节作用。有研究显示，人体中存在GnRHⅠ和GnRHⅡ亚型，且具有Ⅰ型和Ⅱ型GnRH受体。GnRHⅡ对生殖行为及生殖组织具有调控作用，且对神经发育可能也具有调节功能，本文就此做一综述。
出处
《中华妇产科杂志》
CAS
CSCD
北大核心
2008年第11期871-872,共2页
Chinese Journal of Obstetrics and Gynecology
参考文献13
-
1Kah O, Lethimonier C, Somoza G, et al. GnRH and GnRH receptors in metazoa: A historical, comparative, and evolutive perspective. Gen Comp Endocrinol,2007, 153: 346-364.
-
2Millar RP, Lowe S, Conklin DC, et al. A novel mammalian receptor for the evolutionarily conserved type Ⅱ gonadotropinreleasing hormone. Proc Natl Acad Sci U S A, 2001,98: 9636- 9641.
-
3Millar RP. GnRH Ⅱ and type Ⅱ GnRH receptors. Trends Endocrinol Metab, 2003, 14:35-43.
-
4Tsutsumi M, Zhou W, Millar RP, et al. Cloning and functional expression of a mouse gonadotropin-releasing hormone receptor. Mol Endocrinol, 1992,6 : 1163-1169.
-
5Andreu-Vieyra CV, Buret AG, Habibi HR. Gonadotropinreleasing hormone induction of apoptosis in the testes of goldfish Carassius auratus. Endocrinology,2005,146 : 1588-1596.
-
6Neill JD, Wayne Duck L, Sellers JC, et al. A gonadotropinreleasing hormone GnRH receptor specific for GnRH Ⅱ in primates. Biochem Biophys Res Commun, 1999,282 : 1012-1018.
-
7Millar RP, Pawson AJ, Morgan K, et al. Diversity of actions of GnRHs mediated by ligand-induced selective signaling. Front Neuroendoerino1,2008,29 : 17-35.
-
8Kauffman AS. Emerging functions of gonadotropin-releasing hormone Ⅱ in mammalian physiology and behaviour. J Neuroendocrinol, 2004,16:794-806.
-
9Barnett DK, Bunnell TM, Millar RP, et al. Gonadotropin-releasing hormone Ⅱ stimulates female sexual behavior in marmoset monkeys. Endocrinology, 2006, 147:615-623.
-
10Grundker C, Gtlnthert AR, Millar RP, et al. Expression of gonadotropin-releasing hormone Ⅱ ( GnRH-Ⅱ ) receptor in human endometrial and ovarian cancer cells and effects of GnRH-Ⅱ on tumor cell proliferation. J Clin Endocrinol Metab, 2002, 87: 1427 -1430.
-
1姚兵,黄威权,蒲若蕾,孙岚,张荣庆,王雷.大鼠消化道促性腺激素释放激素受体mRNA的原位杂交研究[J].解剖学报,2000,31(3):250-252. 被引量：8
-
2张河川.宫颈炎患者生殖行为、婚姻质量及情绪的研究[J].中国公共卫生,2004,20(5):630-630. 被引量：4
-
3任海珍.年轻女性应小心甲状腺疾病[J].大家健康,2014,0(10):64-64.
-
4蒋风艳,王孟龙.促性腺激素释放激素类似物在不孕症中的应用[J].广西医科大学学报,1995,12(1):176-179.
-
5宋永熙.阿拉瑞林治疗子宫内膜异位症临床疗效观察[J].中华临床医药杂志（北京）,2003,4(24):108-108.
-
6徐延华,韩爱卿,杨钟莉.卵巢早衰患者骨密度、骨钙素水平观察[J].山东医药,2005,45(11):20-20. 被引量：1
-
7病理妊娠(异常妊娠)[J].国外科技资料目录（医药卫生）,2000(5):109-111.
-
8邹洋,吴静.小心布鲁氏菌病[J].健康,2013(4):76-77.
-
9宫美轩,丛德红.中西医结合治疗青春期功能失调性子宫出血51例分析[J].中国实用医药,2009,4(21):170-171. 被引量：2
-
10姚兵,黄威权,孙岚.大鼠消化道促性腺激素释放激素受体的免疫组织化学研究[J].解剖学报,1999,30(2):152-154. 被引量：24
