耐力运动和高脂膳食对大鼠骨骼肌表型的影响
被引量:1
摘要
目的探讨耐力运动和高脂膳食对骨骼肌表型影响。方法雄性SD大鼠(150~180g)40只随机等分成4组:对照组、运动组、高脂组、运动高脂组。运动大鼠进行6周的无坡度跑台训练(28m/min)。第6周取比目鱼肌(SOL)和趾长伸肌(EDL)进行分析。纤维类型用肌球蛋白重链(MHC)电泳和ATPase染色分析。结果耐力运动时大鼠比目鱼肌纤维向慢肌转换,但不影响EDL;耐力运动后摄入高脂膳食倾向降低耐力运动升高的SOLMHC1型比例。耐力运动和高脂膳食对EDL质量有交互影响。结论耐力运动和高脂膳食影响骨骼肌表型,且具有肌肉特异性。
出处
《广东医学》
CAS
CSCD
北大核心
2008年第12期1978-1980,共3页
Guangdong Medical Journal
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