期刊文献+

消化道肿瘤患者肿瘤标志物测定水平的相关分析 被引量:3

下载PDF
导出
摘要 目的对不同的消化道肿瘤患者选择特异性强灵敏度高的肿瘤标志物进行联合测定,以达到提高临床诊断的准确性,并作为治疗和疗效监测的重要指标。方法选择45例正常人和182例肿瘤患者按不同临床诊断选择进行AFP、CEA、CA19-9、CA12-5及SF血清含量的测定,均采用化学发光法。结果不同肿瘤标志物在不同肿瘤中的含量差异有显著性,特异性强的肿瘤标志物均明显增高,而广谱的肿瘤标志物敏感性强但特异性不高。结论根据临床初步诊断选择特异性强敏感度高的主要肿瘤诊断标志物外,可同时选择其他与之相关性强的肿瘤标志物进行联合测定以提高诊断率。
出处 《广东医学》 CAS CSCD 北大核心 2008年第12期2048-2049,共2页 Guangdong Medical Journal
  • 相关文献

参考文献3

  • 1SOLETORMOS G, NIELSEN D, SCHIOLER H, et al. Monitoring different stages of breast cancer using tumor markers Ca15 - 3, CEA and TPA[J]. Eur J Cancer, 2004, 40: 481.
  • 2SASAKI A, KAWANO K, INOMATA M, et al. Value of serum carbohydrate antigen 19 - 9 for Predicting ertrahepatic metastasis in patients will liver metastasis from colorectal carcinoma [ J ]. Hepatogastruenterolgy, 2005, 52: 1814.
  • 3韦振元,王洁,杨永青.CA系列对恶性肿瘤诊断临床表达的价值[J].放射免疫学杂志,2002,15(2):84-86. 被引量:23

二级参考文献8

  • 1[1]Makovitzky J,GotZe S.Immunohistochemical investigation with carbohydrate monoclonal antibodies in cystic fibrosis.Anticancer Res 2000; 20:5121
  • 2[2]Toki T,Kubota J,Lu X,et al.Immunohistochemical analysis of CA125,CA19-9 and Ki-67 in stage Ⅲ or Ⅳ endometriosis: positive correlation between serum CA125 level and endometriotic epithelial cell.Acta Obstet Gynecol Scand 2000;79:771
  • 3[3]Liu JW,Chen YM,Chao Y,et al.Continuous infusion cisplatin and etoposide chemotherapy for cancer of unknown primary site (CUPS) in taiwan,a region with a high prevalence of endemic viral infections,Tpn J Clin Oncol 1998; 28:431
  • 4[4]Kimura Y,Fujjii T,Hamamoto K,et al.Serum CA125 level is a good prognostic indicator in lung cancer.Br J Cancer 1990; 62:676
  • 5[5]Frebourg J,Bercoff E,Monchon N,et al.The evaluation of CA199 antigen level in the early detection of pancreatic cancer.Cancer 1988; 62:2287
  • 6[6]Watanabe M,Chigusa M,Takahashi H,et al.High level of CA19-9,CA50 and CEA-Producible human cholangio carcinoma cell line Changes in the secretion ratios in vitro or in viro.In Vitro Cell Dev Biol Ainm 2000; 36:104
  • 7[7]Xu Y,Kimura.N,Yoshida R,et al.Immunohistochemical study of Mucl,Muc2 and human gastric mucin in breast carcinoma: relationship with prognostic factors.Oncol Rep 2001; 8:1177
  • 8[8]Dupont WD,Parl FF.Breast cancer risk associated with proliferative breast disease and atypical hyperplasia.Cancer 1993;71:1258

共引文献22

同被引文献24

引证文献3

二级引证文献9

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部