中药汤剂灌肠治疗肾综合征出血热少尿期的疗效观察

Observation on the Effect of Chinese Decoction in the Treatment of Hemorrhagic Fever with Renal Syndrome at Oliguric Stage

目的:观察中药加减生大黄汤结肠灌注治疗肾综合征出血热少尿期的疗效与不良反应。方法:所有128例患者均在内科综合治疗的基础上,治疗组66例采用加减生大黄汤结肠灌注,每天3次,当每天尿量>1500ml时,每天2次,连用2周,对照组62例采用传统的甘露醇灌肠治疗,每天3次,当每天尿量>1500ml时,每天2次,共用2周。结果:治疗组总效率为97.27%,对照组总有效率为83.88%,治疗组明显高于对照组(P<0.05)。结论:中药加减生大黄汤结肠灌注治疗肾综合征出血热少尿期效果好,可以明显缩短少尿期,改善症状,未见不良反应。

Objective： To observe the effect of Chinese decoction in the treatment of hemorrhagic fever with renal syndrome. Methods： A total of 128 patients were divided into two groups： control group and treatment group. Patients in the treatment group were treated for 2 weeks with colon perfusion of Chinese decoction for 3 times a day, and twice a day ff the urine exceeded 1500 ml per day. Patients in the control group were treated for 2 weeks with colon perfusion of mannitol for 3 times a day, and twice a day if the urine exceeded 1500 ml per day. Results： The total effective rate in treatment group was 97.27%, much higher than the 83.88% in the control group. Conclusion： Chinese decoction has good therapeutic effect in the treatment of hemorrhagic fever with renal syndrome. It can shorten obviously the oliguric stage with no side effects.