CRP、WBC和ESR联合检测在儿童感染性疾病中应用及意义

The application and significance of CRP, WBC and ESR detection in children infectious disease

目的探讨血清中C-反应蛋白(CRP)、白细胞(WBC)、血沉(ESR)的检测对儿童早期感染鉴别诊断的价值。方法分为细菌感染组35例、病毒感染组28例和对照组20例,分别采用CRP快速分析仪、全自动血球计数仪及ESR测定仪检测。结果细菌感染组CRP、WBC、ESR明显高于对照组,差异非常显著(P<0.01);细菌感染组与病毒感染组比较CRP、WBC均有非常显著性差异(P<0.01),但ESR无显著差异(P>0.05);病毒感染组CRP、WBC与对照组无显著差异(P>0.05),ESR明显升高,与对照组有非常显著性差异(P<0.01)。结论小儿急性感染时,CRP、WBC的检测有助于疾病早期鉴别诊断,对于细菌感染和病毒感染的鉴别诊断有重要价值,而ESR阳性率低,对细菌感染和病毒感染早期鉴别作用不明显。

Objective To discuss the value of detection of CRP, WBC and ESR in differential diagnosis of early bacterial and virus infections in children. Methods All of the specimen were examined by CRP rapid Analyzer, automatic hematology analyzer and ESR Analyzer respectively. Results The results of CRP,WBC and ESR in bacterial infections group were obviously higher than that of the control one （P〈0.01）. The levels of CRP and WBC were significandy different between bacterial infection group and virus infections group （P〈0.01）. Compared with the bacterial group the level of CRP and WBC ESR in viral infection group was not signfieant （P〉0.05）. Conclusion Detection of CRP and WBC is valuable for differential diagnosis of early acute infections in children, especially in bacterial and viral nfection .